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Lasix (furosemide) Dosage

Tablets 20 mg, 40 mg, 80 mg, 100 mg and Oral Solution.

Pediatric Patients: The usual initial dose of oral furosemide in pediatric patients is 2 mg/kg body weight, given as a single dose. If the diuretic response is not satisfactory after the initial dose, dosage may be increased by 1 or 2 mg/kg no sooner than 6 to 8 hours after the previous dose. Doses greater than 6 mg/kg body weight are not recommended. For maintenance therapy in pediatric patients, the dose should be adjusted to the minimum effective level.

Hypertension Therapy should be individualized according to the patient's response to gain maximal therapeutic response and to determine the minimal dose needed to maintain the therapeutic response.

Fluid Retention - You will probably be started at a single dose of 20 mg to 80 mg dose. If needed, the same Lasix dose can be repeated 6 to 8 hours later, or the lasix dose may be increased. Your doctor may raise the lasix dosage by lasix 20 mg or lasix 40 mg with each successive administration-- each 6 to 8 hours after the previous dose - until the desired effect is achieved. This lasix dosage is then taken once or twice daily thereafter. Your doctor should monitor you carefully using laboratory tests. The maximum daily dose is 600 mg.

Lasix Dosage in High Blood Pressure Treatment - The usual starting dose is 80 mg per day divided into 2 doses. Your doctor will adjust the dosage and may add other high blood pressure medications if Lasix is not enough.

LASIX DOSAGE FOR CHILDREN - The usual initial dose is 2 mg per 2.2 pounds of body weight given in a single oral dose. The doctor may increase subsequent doses by 1 to 2 mg per 2.2 pounds. Doses are spaced 6 to 8 hours apart. A child's dosage will be adjusted to the lowest needed to achieve maximum effect, and should not exceed 6 mg per 2.2 pounds.

If you miss a dose of Lasix - Take the forgotten dose of Lasix as soon as you remember. If it is almost time for your next Lasix dose, skip the missed dose and go back to your regular schedule. Never take 2 Lasix dose at the same time.

Lasix Storage instructions - Keep Lasix in the container it came in, tightly closed, and away from direct light. Store Lasix at room temperature.

Lasix Indications and usage

Edema - LASIX is indicated in adults and pediatric patients for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. LASIX is particularly useful when an agent with greater diuretic potential is desired.

Hypertension - Oral LASIX may be used in adults for the treatment of hypertension (High Blood Pressure) alone or in combination with other antihypertensive agents. Hypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with LASIX alone.

Lasix Contraindications

LASIX is contraindicated in patients with anuria and in patients with a history of hypersensitivity to furosemide.

LASIX (furosemide) is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose schedule must be adjusted to the individual patient's needs. (See DOSAGE AND ADMINISTRATION.)

Lasix Precautions

Take Lasix exactly as prescribed by your doctor. Your doctor will adjust the dosages of this strong diuretic to meet your specific needs.

Excessive diuresis may cause dehydration and blood volume reduction with circulatory collapse and possibly vascular thrombosis and embolism, particularly in elderly patients. As with any effective diuretic, electrolyte depletion may occur during LASIX therapy, especially in patients receiving higher doses and a restricted salt intake. Hypokalemia may develop with LASIX , especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids or ACTH. Digitalis therapy may exaggerate metabolic effects of hypokalemia, especially myocardial effects.

All patients receiving LASIX therapy should be observed for these signs or symptoms of fluid or electrolyte imbalance (hyponatremia, hypochloremic alkalosis, hypokalemia, hypomagnesemia or hypocalcemia): dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pains or cramps, muscular fatigue, hypotension, oliguria, tachycardia, arrhythmia, or gastrointestinal disturbances such as nausea and vomiting. Increases in blood glucose and alterations in glucose tolerance tests (with abnormalities of the fasting and 2-hour postprandial sugar) have been observed, and rarely, precipitation of diabetes mellitus has been reported.

Asymptomatic hyperuricemia can occur and gout may rarely be precipitated.

Patients allergic to sulfonamides may also be allergic to LASIX . The possibility exists of exacerbation or activation of systemic lupus erythematosus.

As with many other drugs, patients should be observed regularly for the possible occurrence of blood dyscrasias, liver or kidney damage, or other idiosyncratic reactions.

Simultaneous administration of sucralfate and LASIX tablets may reduce the natriuretic and antihypertensive effects of LASIX . Patients receiving both drugs should be observed closely to determine if the desired diuretic and/or antihypertensive effect of LASIX is achieved. The intake of LASIX and sucralfate should be separated by at least two hours.

One study in six subjects demonstrated that the combination of furosemide and acetylsalicylic acid temporarily reduced creatinine clearance in patients with chronic renal insufficiency. There are case reports of patients who developed increased BUN, serum creatinine and serum potassium levels, and weight gain when furosemide was used in conjunction with NSAIDs.

Literature reports indicate that coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of LASIX (furosemide) in some patients by inhibiting prostaglandin synthesis. Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation. Patients receiving both indomethacin and LASIX should be observed closely to determine if the desired diuretic and/or antihypertensive effect of LASIX is achieved.